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In this study, the researchers discovered that immune cells infiltrating the brain from the blood effectively resisted various abnormalities linked to the condition. These cells appear to work in the mind in several methods to counter the negative effects associated with Alzheimer's disease, said Maya Koronyo-Hamaoui, PhD, assistant professor of neurosurgery and biomedical sciences in Cedars-Sinai, and the senior author of this article published in Brain, a journal of Oxford University Press. The increasing incidence of Alzheimer's disease and the lack of any effective therapy make it imperative to explore new strategies, especially those that can target multiple abnormalities in that complicated disease, Koronyo-Hamaoui added. In Alzheimer's disease, a proteins fragment referred to as amyloid-beta builds up at the synapses of neurons – the point where neuron-to-neuron communication occurs.

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