The study-led by David Baltimore.

This study displays how combining an understanding of molecular mechanisms underlying evolution with the comprehensive sequencing data on historical isolates of influenza virus can result in a deeper knowledge of the challenge that virus presents to the population, says Baltimore. Just by marshaling a wide range of available info was it feasible to understand why the virus could all of a sudden tolerate mutations that were previously deleterious.The mutation was found in twenty-six people from eleven family members. All were of Cypriot ancestry. The mutation is believed by The researchers goes back to an individual common ancestor over sixteen generations ago. ‘We believe this mutation accounts for a substantial proportion of kidney disease in the Cypriot human population, both on the island itself and world-wide,’ says Dr Matthew Pickering, a Wellcome Trust Senior Fellow at Imperial College London. ‘It really is a potentially serious illness, but detectable from a simple DNA or blood test easily. ‘ Although scientists do not yet understand how the mutation qualified prospects to disease fully, the researchers believe that the results should help them offer effective genetic counselling to households suffering from the condition.

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